On 10 March 2022, Roche Holdings, Inc. successfully completed its issuance of USD 5 billion in aggregate principal amount of senior notes, consisting of USD 1.25 billion 1.882% Notes due 2024, USD 1 billion 2.132% Notes due 2025, USD 1,25 billion 2.314% Notes due 2027, USD 750 million Floating Rate Notes due 2023, and USD 750 million Floating Rate Notes due 2025. The notes are irrevocably and unconditionally guaranteed by Roche Holding Ltd.

Moreover, on 25 February 2022 Roche Kapitalmarkt AG issued bonds guaranteed by Roche Holding Ltd. The transaction consists of a CHF 1.25 billion tranche due November 2022, a CHF 825 million tranche due February 2027, a CHF 625 million tranche due February 2031 and a CHF 300 million tranche due February 2037.